Publicaciones científicas en Inglés. 2016

Cañón S, Caballero R, Herraiz-Martínez A, Pérez-Hernández M, López B, Atienza , Jalife J, Hove-Madsen L, Delpón E, Bernad A.
miR-208b upregulation interferes with calcium handling in HL-1 atrial myocytes: Implications in human chronic atrial fibrillation.
J Mol Cell Cardiol. 2016 Oct;99:162-173. doi: 0.1016/j.yjmcc.2016.08.012.

Tamargo J
Mechanism of Action of LCZ696
Cardiac Failure Review, 2016;2(1):40-6 doi: 10.15420/cfr.2016:1:1

Rivera-Torres J, Calvo CJ, Llach A, Guzmán-Martínez G, Caballero R, González-Gómez C, Jiménez-Borreguero LJ, Guadix JA, Osorio FG, López-Otín C, Herraiz-Martínez A, Cabello N, Vallmitjana A, Benítez R, Gordon LB, Jalife J, Pérez-Pomares JM, Tamargo J, Delpón E, Hove-Madsen L, Filgueiras-Rama D, Andrés V.
Cardiac electrical defects in progeroid mice and Hutchinson-Gilford progeria syndrome patients with nuclear lamina alterations.
Proc Natl Acad Sci U S A. 2016 Nov 15;113(46):E7250-E7259.

Kirchhof P, Benussi S, Kotecha D, Ahlsson A, Atar D, Casadei B, Castella M, Diener HC, Heidbuchel H, Hendriks J, Hindricks G, Manolis AS, Oldgren J, Popescu BA, Schotten U, Van Putte B, Vardas P; Authors/Task Force Members; Document Reviewers: Agewall S, Camm J, Baron Esquivias G, Budts W, Carerj S, Casselman F, Coca A, De Caterina R, Deftereos S, Dobrev D, Ferro JM, Filippatos G, Fitzsimons D, Gorenek B, Guenoun M, Hohnloser SH, Kolh P, Lip GY, Manolis A, McMurray J, Ponikowski P, Rosenhek R, Ruschitzka F, Savelieva I, Sharma S, Suwalski P, Tamargo JL, et al.
2016 ESC Guidelines for the management of atrial fibrillation developed in collaboration with EACTS: The Task Force for the management of atrial fibrillation of the European Society of Cardiology (ESC)Developed with the special contribution of the European Heart Rhythm Association (EHRA) of the ESCEndorsed by the European Stroke Organisation (ESO).
Europace. 2016 Nov;18(11):1609-1678.PubMed PMID: 27567465.

Tamargo J, Ruilope LM.
Investigational calcium channel blockers for the treatment of hypertension
Expert Opin Investig Drugs. 2016 Oct 4. PubMed PMID: 27696904.

Kirchhof P, Benussi S, Kotecha D, Ahlsson A, Atar D, Casadei B, Castella M, Diener HC, Heidbuchel H, Hendriks J, Hindricks G, Manolis AS, Oldgren J, Popescu BA, Schotten U, Van Putte B, Vardas P, Agewall S, Camm J, Baron Esquivias G, Budts W, Carerj S, Casselman F, Coca A, De Caterina R, Deftereos S, Dobrev D, Ferro JM, Filippatos G, Fitzsimons D, Gorenek B, Guenoun M, Hohnloser SH, Kolh P, Lip GY, Manolis A, McMurray J, Ponikowski P, Rosenhek R, Ruschitzka F, Savelieva I, Sharma S, Suwalski P, Tamargo JL, Taylor CJ, Van Gelder IC, Voors AA, Windecker S, Zamorano JL, Zeppenfeld K.
2016 ESC Guidelines for the management of atrial fibrillation developed in collaboration with EACTS.
Eur J Cardiothorac Surg. 2016 Nov;50(5):e1-e88. PMID: 27663299.

Kirchhof P, Benussi S, Kotecha D, Ahlsson A, Atar D, Casadei B, Castella M, Diener HC, Heidbuchel H, Hendriks J, Hindricks G, Manolis AS, Oldgren J, Popescu BA, Schotten U, Van Putte B, Vardas P; Authors/Task Force Members.; Document Reviewers: Agewall S, Camm J, Baron Esquivias G, Budts W, Carerj S, Casselman F, Coca A, De Caterina R, Deftereos S, Dobrev D, Ferro JM, Filippatos G, Fitzsimons D, Gorenek B, Guenoun M, Hohnloser SH, Kolh P, Lip GY, Manolis A, McMurray J, Ponikowski P, Rosenhek R, Ruschitzka F, Savelieva I, Sharma S, Suwalski P, Tamargo JL, et al.
2016 ESC Guidelines for the management of atrial fibrillation developed in collaboration with EACTS: The Task Force for the management of atrial fibrillation of the European Society of Cardiology (ESC)Developed with the special contribution of the European Heart Rhythm Association (EHRA) of the ESCEndorsed by the European Stroke Organisation (ESO).
Eur Heart J. 2016 Aug 27. pii: ehw210. PubMed PMID: 27567408.

Zamorano JL, Lancellotti P, Rodriguez Muñoz D, Aboyans V, Asteggiano R, Galderisi M, Habib G, Lenihan DJ, Lip GY, Lyon AR, Lopez Fernandez T, Mohty D, Piepoli MF, Tamargo J, Torbicki A, Suter TM; Authors/Task Force Members.; ESC Committee for Practice Guidelines (CPG).
2016 ESC Position Paper on cancer treatments and cardiovascular toxicity developed under the auspices of the ESC Committee for Practice Guidelines: The Task Force for cancer treatments and cardiovascular toxicity of the European Society of Cardiology (ESC).
Eur Heart J. 2016 Sep 21;37(36):2768-2801. PubMed PMID: 27567406.

Zamorano JL, Lancellotti P, Rodriguez Muñoz D, Aboyans V, Asteggiano R, Galderisi M, Habib G, Lenihan DJ, Lip GY, Lyon AR, Lopez Fernandez T, Mohty D, Piepoli MF, Tamargo J, Torbicki A, Suter TM, Zamorano JL, Aboyans V, Achenbach S, Agewall S, Badimon L, Barón-Esquivias G, Baumgartner H, Bax JJ, Bueno H, Carerj S, Dean V, Erol Ç, Fitzsimons D, Gaemperli O, Kirchhof P, Kolh P, Lancellotti P, Lip GY, Nihoyannopoulos P, Piepoli MF, Ponikowski P, Roffi M, Torbicki A, Vaz Carneiro A, Windecker S; Authors/Task Force Members; ESC Committee for Practice Guidelines (CPG); Document Reviewers.
2016 ESC Position Paper on cancer treatments and cardiovascular toxicity developed under the auspices of the ESC Committee for Practice Guidelines: The Task Force for cancer treatments and cardiovascular toxicity of the European Society of Cardiology (ESC).
Eur J Heart Fail. 2016 Aug 27. doi: 10.1002/ejhf.654. [Epub ahead of print] PubMed PMID: 27565769.

Schmidt M, Lamberts M, Olsen AM, Fosbøll E, Niessner A, Tamargo J, Rosano G, Agewall S, Kaski JC, Kjeldsen K, Lewis BS, Torp-Pedersen C.
Cardiovascular safety of non-aspirin non-steroidal anti-inflammatory drugs: review and position paper by the working group for Cardiovascular Pharmacotherapy of the European Society of Cardiology.
Eur Heart J Cardiovasc Pharmacother. 2016 Apr;2(2):108-18. doi: 10.1093/ehjcvp/pvv054. PubMed PMID: 27533522.

Zannad F, Stough WG, Lipicky RJ, Tamargo J, Bakris GL, Borer JS, Alonso García Mde L, Hadjadj S, Koenig W, Kupfer S, McCullough PA, Mosenzon O, Pocock S, Scheen AJ, Sourij H, Van der Schueren B, Stahre C, White WB, Calvo G.
Assessment of cardiovascular risk of new drugs for the treatment of diabetes mellitus: risk assessment vs. risk aversion.
Eur Heart J Cardiovasc Pharmacother. 2016 Jul;2(3):200-5. doi: 10.1093/ehjcvp/pvw007. Epub 2016 Apr 3. Review. PubMed PMID: 27418973; PubMed Central PMCID: PMC4907355.

Ambrosio G, Komajda M, Mugelli A, Lopez-Sendón J, Tamargo J, Camm J.
Management of stable angina: A commentary on the European Society of Cardiology guidelines.
Eur J Prev Cardiol. 2016 Sep;23(13):1401-12. doi: 10.1177/2047487316648475. Epub 2016 May 24. PubMed PMID: 27222385.

Romero M, Jiménez R, Toral M, León-Gómez E, Gómez-Gúzman M, Sánchez M, Zarzuelo MJ, Rodríguez-Gómez I, Rath G, Tamargo J, Pérez-Vizcaíno F, Dessy C, Duarte J.
Vascular and Central Activation of Peroxisome Proliferator-Activated Receptor-β Attenuates Angiotensin II-Induced Hypertension: Role of RGS-5. J
Pharmacol Exp Ther. 2016 Jul;358(1):151-63. doi: 10.1124/jpet.116.233106. Epub 2016 Apr 27. PubMed PMID: 27189971.

Toral M, Romero M, Jiménez R, Robles-Vera I, Tamargo J, Martínez MC, Pérez-Vizcaíno F, Duarte J.
Role of UCP2 in the protective effects of PPARβ/δ activation on lipopolysaccharide-induced endothelial dysfunction.
Biochem Pharmacol. 2016 Jun 15;110-111:25-36. doi: 10.1016/j.bcp.2016.05.004. Epub 2016 May 12. PubMed PMID: 27179975.

Schmidt M, Lamberts M, Olsen AM, Fosbøll E, Niessner A, Tamargo J, Rosano G, Agewall S, Kaski JC, Kjeldsen K, Lewis BS, Torp-Pedersen C.
Cardiovascular safety of non-aspirin non-steroidal anti-inflammatory drugs: review and position paper by the working group for Cardiovascular Pharmacotherapy of the European Society of Cardiology.
Eur Heart J. 2016 Apr 1;37(13):1015-23. doi: 10.1093/eurheartj/ehv505.

Ambrosio G, Tamargo J, Grant PJ.
Non-haemodynamic anti-anginal agents in the management of patients with stable coronary artery disease and diabetes: A review of the evidence.
Diab Vasc Dis Res. 2016 Mar;13(2):98-112. doi:10.1177/1479164115609028.

Matamoros M, Pérez-Hernández M, Guerrero-Serna G, Amorós I, Barana A, Núñez M, Ponce-Balbuena D, Sacristán S, Gómez R, Tamargo J, Caballero R, Jalife J, Delpón E.
Nav1.5 N-terminal domain binding to α1-syntrophin increases membrane density of human Kir2.1, Kir2.2 and Nav1.5 channels.
Cardiovasc Res. 16 May 15;110(2):279-90. doi: 10.1093/cvr/cvw009.

Este trabajo ha merecido una Editorial en la revista Cardiovascular Research:

Mohler PJ, Abriel H. Complexity of cardiac ion channel macromolecular complexes. Cardiovasc Res. 2016 May 15;110(2):163-4. doi: 10.1093/cvr/cvw055.

Pérez-Hernández M, Matamoros M, Barana A, Amorós I, Gómez R, Núñez M, Sacristán S, Pinto Á, Fernández-Avilés F, Tamargo J, Delpón E, Caballero R.
Pitx2c increases in atrial myocytes from chronic atrial fibrillation patients enhancing IKs and decreasing ICa,L.
Cardiovasc Res. 2016 Mar 1;109(3):431-41. doi: 10.1093/cvr/cvv280.

Este trabajo ha merecido una Editorial en la revista Cardiovascular Research:

Li N, Dobrev D, Wehrens XH. PITX2: a master regulator of cardiac channelopathy in atrial fibrillation? Cardiovasc Res. 2016 Mar 1;109(3):345-7. doi: 10.1093/cvr/cvw008.

Ferrari R, Bertini M, Blomstrom-Lundqvist C, Dobrev D, Kirchhof P, Pappone C, Ravens U, Tamargo J, Tavazzi L, Vicedomini GG.
An update on atrial fibrillation in 2014: From pathophysiology to treatment.
Int J Cardiol. 2016 Jan 15;203:22-9. doi: 10.1016/j.ijcard.2015.10.089.